The second such HIV patient has been identified in the world who may have become free from the virus without the use of 'antiretroviral' drugs.
Scientists gave this information on Tuesday. The finding, published in the journal Annals of Internal Medicine, revealed that the patient was suffering from HIV and was not receiving any treatment. His study of more than 1.5 billion blood and tissue cells found no evidence of a viral genome. The immunity weakens due to HIV i.e. Human Immunodeficiency Virus and after a time the body's immune system stops working. After this, many types of infections occur and the patient may even die.
The international team noted that if researchers can understand the immune mechanisms underlying this response, they may be able to develop treatments that can prepare the immune systems of others to replicate these responses in cases of HIV infection. . Scientists have not revealed the identity of this patient, they have named the patient as Esperanza patient. He said the virus has the ability to effectively protect itself from anti-HIV drugs and the body's immune responses. Surprisingly, in such a case, the scientists who had identified the first patient, the same scientists have identified the second patient.
The researchers said that HIV stores its genome patterns in the DNA or genetic material of cells, also known as viral storage, during infection. In such a situation, the virus effectively escapes with anti-HIV drugs and the body's immune response, he added. In most people, new viral particles are constantly being made from this store. Anti-retroviral therapy (ART) drugs stop the production of new viruses, but these drugs do not have the ability to kill the entire pool of viruses. Because of this, new particles of the virus keep forming in most of the patients. Due to these, patients have to take medicine daily to weaken the virus.
Under 'anti-retroviral therapy' (ART), the new virus can be stopped from forming but the stock cannot be completely eliminated. Due to this, daily treatment is required to control the virus. In their previous study, the scientists identified a patient whose genome did not contain the HIV viral sequence. This indicates that his immune system may have depleted the HIV stockpile.
